site stats

Tsc1 antibody

WebNov 10, 2024 · Tsc1 was immunoprecipitated from HEK293 cell lysates using anti-Tsc1 antibody and immunoblotted with indicated antibodies to confirm chaperone, co-chaperone, and client protein interaction. IgG was used as control. FLAG-tagged Hsp90α N-, M-, and C-domains were transiently expressed and immunoprecipitated from HEK293 cells. WebMedium consistency between antibody staining and RNA expression data. Medium consistency between antibody staining and RNA expression data. WESTERN BLOT i …

Mouse Anti-Yeast LCB2 Antibody (CBMOAB-02047CR)

WebFeb 4, 2024 · Tuberous sclerosis complex subunit 1 (TSC1) and 2 (TSC2) are frequently mutated in non–small cell lung cancer (NSCLC), however, their effects on antitumor immunity remained unexplored.A CRISPR screening in murine Kras G12D /Trp53 −/− (KP) model identified Tsc1 and Tsc2 as potent regulators of programmed cell death ligand 1 … WebApr 11, 2024 · TSC1 and TSC2 are also involved in the G2/M transition of the cell cycle through their interactions with CDK1 and cyclin B1. TSC1 has also been shown to interact with Factin and ERM (EzrinRadixinMoesin) proteins, implying a role in the modulation of cell adhesion and morphology. Human TSC1 Antibody forcep recto https://theproducersstudio.com

Anti TSC1 Antibody Bio-Rad

Web5.2 TSC1–TSC2 complex. TSC1 and TSC2 genes were identified in 1997 and 1993 as the genetic loci mutated in the disease known as tuberous sclerosis complex (TSC) (European TSC Consortium, 1993; van Slegtenhorst et al., 1997). These genes’ products are two proteins, TSC1 and TSC2, which do not share any homology between them, and very little ... WebUrothelial carcinoma represents one of the most prevalent types of cancer worldwide, and its incidence is expected to grow. Although the treatment of the advanced disease was based on chemotherapy for decades, the developments of different therapies, such as immune checkpoint inhibitors, antibody drug conjugates and tyrosine kinase inhibitors, … WebTSC1 antibody (ABIN1955081). Validated for IHC, ELISA. Tested in Human. Order online. English ... Comparison List Basket Phone: +1 877 302 8632 Fax: +1 888 205 9894 (Toll-free) E-Mail: [email protected]. Home Antibodies ELISA Kits Primary Antibodies. Monoclonal Antibodies; Polyclonal Antibodies; Recombinant ... elizabeth short american horror story hotel

TSC1 Mouse anti-Human, Clone: OTI2B2, liquid, TrueMAB™

Category:TSC1 Polyclonal Antibody (A300-316A) - thermofisher.com

Tags:Tsc1 antibody

Tsc1 antibody

Bladder tumour-derived somatic TSC1 missense mutations cause …

WebLearn more about Anti-TSC1 Rabbit Polyclonal Antibody (PE (Phycoerythrin)). We enable science by offering product choice, services, process excellence and our people make it happen. WebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20130. Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse samples. Supplied as 100 µg …

Tsc1 antibody

Did you know?

WebTSC1 antibody; see all. Images. Western blot - Anti-TSC-1 antibody (ab217328) All lanes : Anti-TSC-1 antibody (ab217328) at 0.5 µg/ml Lane 1 : Colo320 whole cell lysate Lane 2 : … WebNov 12, 2024 · TSC1/2-mutated PEComas sometimes respond to mTOR-inhibition therapy , but these drugs are mechanistically believed to be inefficient in TFE3-altered PEComa. MET-inhibitors, on the other hand, are active in alveolar soft part sarcoma with TFE3 rearrangement [ 20 ], a rare subtype of soft-tissue sarcoma, and could constitute a …

WebJul 25, 2005 · The polyclonal and monoclonal TSC1 antibodies were gifts of V. Ramesh (Massachusetts General Hospital, Boston, MA). Affinity-purified antibody against GST was prepared from anti-GST serum using GST immobilized on glutathione-Sepharose as an affinity matrix. The mouse monoclonal α-vinculin antibody was obtained from Upstate … WebTSC2 Antibody: Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine …

WebProduct Description. Mouse anti Human TSC1 antibody recognizes TSC1, also known as hamartin and tuberous sclerosis 1 protein. TSC1 encodes a growth inhibitory protein … WebPolyclonal Antibody for studying Hamartin/TSC1. Cited in 74 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Hamartin/TSC1 Antibody (CST #4906) is ready to ship.

WebSep 1, 2010 · The TSC1 and TSC2 polyclonal antibodies used in this study were purchased from Santa Cruz Biotechnology and used at the manufacturer's recommended dilutions. The anti-T7Tag monoclonal antibody was from Novagen. …

WebProduct Description. Mouse anti Human TSC1 antibody recognizes TSC1, also known as hamartin and tuberous sclerosis 1 protein. TSC1 encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in TSC1 have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript ... elizabeth sherwood ritWebAntibody was affinity purified using an epitope specific to TSC1 immobilized on solid support. The epitope recognized by A300-316A maps to a region between residue 1100 and the C-terminus (residue 1164) of human tuberous sclerosis 1 using the numbering given in Swiss-Prot entry Q92574 (GeneID 7248). elizabeth shorts bodyWebApr 7, 2008 · Sensitivity and specificity of a rabbit monoclonal anti-TSC1 antibody was confirmed by staining of paraffin-embedded pellets of TSC1-null HCV29 cells and HCV29 in which wild-type TSC1 had been re-expressed (Fig. 7 A and D). Normal ureter showed strong cytoplasmic TSC1 expression in the urothelium (Fig. 7 E). forcep recto anterior finoWebFeb 5, 2024 · How activated B cells build biosynthetic pathways and organelle structures necessary for subsequent robust antibody secretion is still unclear. The dominant model holds that nascent plasma cells adapt to increased antibody synthesis by activating the unfolded protein response (UPR) under the control of the transcription factor Xbp1. forcep reductionWebAug 24, 2012 · The endogenous interaction of TBC1D7 with the TSC1-TSC2 complex was confirmed in reciprocal immunoprecipitations with a panel of six unique antibodies to TSC1 or TSC2, along with an antibody raised against TBC1D7 (Figure 1 B), the specificity of which was confirmed through siRNA-mediated knockdown of TBC1D7 (Figure S1 E).TBC1D7 … forcep recto anteriorWebInvitrogen Anti-TSC1 Polyclonal, Catalog # PA5-20131. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF) applications. This antibody reacts with Human, Mouse, Rat … elizabeth shorts childhoodWebThis TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S505 of human TSC1. … elizabeth shoup